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Updated: Mar 20, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Novel imaging in renal cell carcinoma
Katherine M Krajewski1, Atul B Shinagare
1Department of Imaging, Dana-Farber Cancer Institute; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, USA.
Novel imaging techniques offer new ways to characterize renal cell carcinoma (RCC) subtypes and predict treatment response. Further standardization and validation are crucial for clinical adoption of these promising renal cell carcinoma biomarkers.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Renal cell carcinoma (RCC) is a complex cancer with diverse subtypes and behaviors.
- Accurate characterization of RCC is essential for effective treatment planning.
- Current diagnostic methods may be complemented by advanced imaging biomarkers.
Purpose of the Study:
- To review novel imaging techniques and analytical methods for characterizing renal cell carcinoma.
- To correlate imaging biomarkers with genetic and histologic features of RCC.
- To assess the potential of these biomarkers in predicting treatment response and aggressiveness.
Main Methods:
- Exploration of texture analysis and radiogenomics in RCC.
- Review of modality-specific advancements in medical imaging for RCC.
- Introduction of novel analytical methods for quantitative and qualitative imaging biomarker assessment.
Main Results:
- Emerging imaging biomarkers show promise in differentiating RCC subtypes.
- Radiogenomic approaches correlate imaging features with genetic profiles.
- Advanced techniques aid in assessing tumor aggressiveness and therapy responsiveness.
Conclusions:
- Novel imaging techniques and analytical methods enhance the characterization of renal cell carcinoma.
- Standardization and validation are necessary for clinical implementation of these RCC biomarkers.
- These biomarkers hold potential to complement traditional pathology and improve patient management.
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