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Updated: Sep 27, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
The long-term significance of neurological findings at toddler's age
Insights
This study followed infants to track neurological development. Minor neurological dysfunction (MND) was reliably detected by 18 months, with its frequency increasing with age.
Area of Science:
- Pediatric Neurology
- Developmental Neuroscience
- Child Health
Background:
- Longitudinal studies are crucial for understanding developmental trajectories in children.
- Identifying early indicators of neurological dysfunction aids in timely intervention.
- Minor neurological dysfunction (MND) can impact a child's development and learning.
Purpose of the Study:
- To longitudinally assess neurological development in infants.
- To determine the reliability of detecting neurological handicaps and MND at different ages.
- To analyze changes in neurological classification over time.
Main Methods:
- Neurological re-examinations of 80 neurologically abnormal infants at 1.5, 4, and 9 years.
- Follow-up examinations of 80 normal newborns at 1.5 and 4 years.
- Focus on the identification and tracking of minor neurological dysfunction (MND).
Main Results:
- Neurological handicap was reliably identified by 18 months of age.
- The frequency of minor neurological dysfunction (MND) demonstrated an increase with advancing age.
- Changes in neurological classification were observed throughout the follow-up period.
Conclusions:
- Early detection of neurological handicap is feasible by 18 months.
- Minor neurological dysfunction (MND) prevalence appears to increase during childhood.
- Longitudinal neurological assessment provides valuable insights into developmental changes.
Abstract:
Eighty neurologically abnormal infants were re-examined neurologically at 1 1/2, 4 and 9 years of age. Eighty normal newborn were seen again at 1 1/2 and 4 years. Special attention was paid to the presence of minor neurological dysfunction (MND). Changes in neurological classification occurring during the period of time in question are discussed. Neurological handicap could be spotted reliably at 18 months. The frequency of MND increases with age, however.
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