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Updated: Mar 20, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
The changes in complete blood count in thyroid cancer patients treated with radioactive iodine ablation therapy
Bircan Sönmez1, İsmail Doğan, Canan Yavruoğlu
1Department of Nuclear Medicine, Karadeniz Technical University School of Medicine, Trabzon, Turkey Phone: +90 462 377 57 42
Objective:
The aim of this study was to evaluate the effect of radioactive iodine (RAI) ablation therapy on the complete blood count (CBC) in thyroid cancer patients.
Methods:
One hundred sixty four patients undergoing RAI ablation therapy after total thyroidectomy were included. CBC results were available from the patients' medical records at the time of ablation and at the 1st, 6th, and 12th months after RAI therapy.
Results:
Hemoglobin (Hb), white blood cell (WBC) and platelet (Plt) values were significantly lower than baseline at 1 month after treatment (p <0.0001). Hb and WBC values were increased at the 6th month and at the 1st year. Plt values increased at the 6th month but had decreased again at the 1st year. The values were usually in normal ranges except in the patients with low pretreatment Hb and WBC values.
Conclusion:
RAI ablation therapy in thyroid cancer patients is a safe treatment modality without any serious or persistent hematological side effects.
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