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Updated: Mar 20, 2026

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells
Published on: December 27, 2017
Acquired pure megakaryocytic aplasia successfully treated with cyclosporine
Halima El Omri1, Firyal Ibrahim, Ruba Yasin Taha
1Department of Hematology and Bone Marrow Transplant Al Amal Hospital - Hamad Medical Corporation P.O. Box 3050 Doha, Qatar Phone: +974- 4397857
Abstract:
Acquired pure megakaryocytic aplasia is a rare hematological disorder characterized by thrombocytopenia with absent or markedly reduced megakaryocytes in the bone marrow. We report a case of a 25-year-old male diagnosed as acquired pure megakaryocytic aplasia. Treatment with prednisone and intravenous immunoglobulin failed, but he was successfully treated with cyclosporine, with complete remission after 90 days and normal platelet count maintained thereafter.

