Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Primary Lymphoid Organs01:16

Primary Lymphoid Organs

16.5K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
16.5K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

10.1K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
10.1K
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

3.7K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
3.7K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.1K
Skin Cancer01:30

Skin Cancer

6.5K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.5K
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

5
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
5

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Immune deficiency/dysregulation-associated lymphoma with an immunophenotype resembling EBV-positive nodal T/NK-cell lymphoma during treatment of follicular lymphoma].

[Rinsho ketsueki] The Japanese journal of clinical hematology·2026
Same author

[PTHrP-producing diffuse large B-cell lymphoma presenting with hypercalcemia at diagnosis].

[Rinsho ketsueki] The Japanese journal of clinical hematology·2026
Same author

Linvoseltamab versus real-world International Myeloma Working Group standard-of-care in triple-class exposed relapsed/refractory multiple myeloma.

Blood cancer journal·2026
Same author

Assessment of Predictive Factors That Shorten Duration of Treatment in Patients With Multiple Myeloma Using AI: Real-World Longitudinal Study Using Data From Medical Data Vision Claims Database.

JMIR cancer·2026
Same author

Successful hemodialysis initiation in acquired hemophilia a managed with susoctocog alfa and emicizumab.

CEN case reports·2025
Same author

Japanese Adult Day Service Nurses' Bathing Decisions for Persons Requiring Long-Term Care: A Focused Ethnography.

International journal of older people nursing·2025

Related Experiment Video

Updated: Mar 20, 2026

Enhancing Tumor Content through Tumor Macrodissection
10:04

Enhancing Tumor Content through Tumor Macrodissection

Published on: February 12, 2022

12.6K

Diffuse large B-cell lymphoma recurring with zosteriform cutaneous lesions.

Ryohei Sumitani1, Keiko Mori, Etsuko Sekimoto

  • 1Department of Hematology, Tokushima Prefectural Central Hospital.

[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|June 7, 2016
PubMed
Summary

A patient with diffuse large B-cell lymphoma (DLBCL) developed skin lesions mimicking herpes zoster. Histopathological examination confirmed these were cutaneous recurrences of DLBCL, not viral infections.

More Related Videos

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

1.4K
Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines
06:38

Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines

Published on: November 8, 2011

41.4K

Related Experiment Videos

Last Updated: Mar 20, 2026

Enhancing Tumor Content through Tumor Macrodissection
10:04

Enhancing Tumor Content through Tumor Macrodissection

Published on: February 12, 2022

12.6K
Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

1.4K
Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines
06:38

Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines

Published on: November 8, 2011

41.4K

Area of Science:

  • Oncology
  • Dermatology
  • Pathology

Background:

  • Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
  • Cutaneous manifestations can occur in DLBCL, but are often misdiagnosed.
  • Early and accurate diagnosis is crucial for effective treatment and patient outcomes.

Observation:

  • A 75-year-old woman with stage IIIA DLBCL, treated with R-CHOP chemotherapy, developed painful, erythematous, nodular skin lesions on her left lower abdomen.
  • Initial suspicion of herpes zoster was treated with valacyclovir, but the lesions progressed.
  • Histopathological examination of skin lesions revealed DLBCL infiltration.

Findings:

  • The patient's skin lesions were diagnosed as zosteriform cutaneous recurrence of DLBCL.
  • This case highlights the importance of considering malignancy in atypical skin presentations.
  • Histopathological confirmation is essential for differentiating cutaneous lymphoma from infectious causes.

Implications:

  • Skin lesions mimicking herpes zoster can represent a recurrence of DLBCL.
  • Prompt histopathological evaluation is critical for accurate diagnosis and management of suspected cutaneous lymphoma.
  • This underscores the need for a high index of suspicion for malignancy in patients with unusual dermatological findings.