Relapsed hydroxychloroquine induced thrombocytopenia in a systemic lupus erythematosus patient

Vanesa Antón Vázquez1, Luis Pascual1, Héctor Corominas2

  • 1Servicio de Medicina Interna, Hospital Moisès Broggi, Sant Joan Despí Barcelona, Barcelona, España.

Hydroxychloroquine is used in the long-term therapy of systemic lupus erythematosus (SLE). Although considered to be a safe treatment, side effects have been documented. An uncommon side effect is thrombocytopenia. In order to establish the diagnosis of thrombocytopenia secondary to Hydroxychloroquine, non-pharmacological causes must be ruled out and it is necessary to determine a recurrence after re-exposure to the drug. We present one case of severe thrombocytopenia occurring in a patient with SLE undergoing treatment with Hydroxychloroquine.

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