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Updated: Mar 20, 2026
07:24
A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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Brilliant cresyl blue staining for screening hemoglobin H disease: Reticulocyte smear
İbrahim Kulaç, Şule Ünal1, Fatma Gümrük
1Hacettepe University, Division of Pediatric Hematology 06100 Ankara, Turkey, Phone: +90 312 305 11 70
Abstract
No abstract available in PubMed .
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Hemoglobin is a globular protein made up of four subunits. Two of these subunits are alpha chains, and the other two are beta chains. Each subunit contains a molecule of heme, which has an iron atom and can bind to oxygen. When an oxygen molecule binds to one heme group, it changes the shape of hemoglobin, making it easier for the other heme groups to bind oxygen as well.
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