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Yaws: towards the WHO eradication target.

Michael Marks1

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Transactions of the Royal Society of Tropical Medicine and Hygiene
|June 9, 2016
PubMed
Summary

The World Health Organization aimed to eradicate yaws by 2020 using mass azithromycin treatments. New challenges like similar ulcers caused by Haemophilus ducreyi and potential animal reservoirs complicate this ambitious goal.

Keywords:
AzithromycinEradicationNeglected Tropical DiseasesTreponema pallidumWorld Health OrganizationYaws

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Area of Science:

  • Global health
  • Infectious diseases
  • Tropical medicine

Background:

  • Yaws eradication was a 2020 target set by the World Health Organization (WHO).
  • Community mass treatment with azithromycin is the primary strategy.
  • Progress has been made in diagnostic test development for yaws.

Purpose of the Study:

  • To review the progress and challenges in the WHO's yaws eradication strategy.
  • To highlight emerging issues impacting the 2020 eradication target.

Main Methods:

  • Review of existing literature and reports on yaws eradication efforts.
  • Analysis of diagnostic test development and validation studies.
  • Examination of epidemiological data and emerging challenges.

Main Results:

  • Azithromycin mass treatment shows promise in interrupting yaws transmission.
  • Development and validation of new diagnostic tools for yaws have advanced.
  • Emerging challenges include ulcers caused by Haemophilus ducreyi and a potential non-human primate reservoir.

Conclusions:

  • The 2020 yaws eradication target remains highly ambitious.
  • Continued challenges necessitate ongoing research and adaptive strategies for disease elimination.