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Updated: Mar 19, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Syncope and Dyspnea and Pulmonary Embolism
1Section of Cardiology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Acute cor pulmonale, a heart condition caused by lung issues, can be fatal if missed. Prompt recognition of electrocardiogram (ECG) signs is crucial for diagnosing pulmonary emboli and preventing death.
Area of Science:
- Cardiology
- Pulmonology
- Medical Diagnostics
Background:
- Acute cor pulmonale is a severe condition often presenting with subtle or non-specific symptoms.
- Pulmonary emboli (PE) are a leading cause of preventable death in hospitalized patients.
- Electrocardiogram (ECG) is a readily available diagnostic tool in emergency settings.
Observation:
- A male patient presented with new onset syncope and dyspnea.
- ECG findings suggestive of acute cor pulmonale were not recognized.
- The patient subsequently died due to undiagnosed pulmonary emboli.
Findings:
- Missed ECG diagnosis of acute cor pulmonale contributed to delayed treatment for pulmonary emboli.
- Failure to identify critical cardiac strain secondary to pulmonary hypertension led to a fatal outcome.
- The case highlights the importance of a high index of suspicion for PE in patients with relevant symptoms.
Implications:
- Emphasizes the need for enhanced training in interpreting ECG for acute cor pulmonale.
- Underscores the critical role of timely diagnosis of pulmonary emboli in preventing mortality.
- Suggests integrating advanced cardiac and pulmonary diagnostic protocols for patients with syncope and dyspnea.
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
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