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Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
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"Puffy hand syndrome".

Mickaël Chouk1, Claire Vidon1, Elise Deveza2

  • 1Department of Rheumatology, CHRU Besançon, boulevard Fleming, 25030 Besançon, France.

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|June 9, 2016
PubMed
Summary
This summary is machine-generated.

Puffy hand syndrome, a rare rheumatologic condition, can occur in intravenous drug users. This syndrome presents as painless, non-pitting hand edema, even after cessation of drug use.

Keywords:
EdemaHandPuffy handToxicomania

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Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Toxicology

Background:

  • Intravenous drug addiction frequently leads to cutaneous and infectious complications.
  • Puffy hand syndrome is a rare rheumatologic manifestation associated with intravenous drug use.
  • The syndrome is characterized by bilateral, painless, non-pitting edema of the hands.

Purpose of the Study:

  • To report two cases of puffy hand syndrome in patients with a history of intravenous drug addiction.
  • To discuss the clinical presentation, diagnostic approach, and potential pathophysiology of this rare condition.

Main Methods:

  • Case report of two patients presenting with puffy hands.
  • Clinical evaluation, including medical history and physical examination.
  • Diagnostic investigations included biological tests, radiological imaging, and ultrasound.

Main Results:

  • Both patients had a history of intravenous drug addiction and presented with bilateral, painless, non-pitting hand edema.
  • Diagnostic investigations were unremarkable, supporting the diagnosis of puffy hand syndrome.
  • One patient experienced improvement in hand edema with nocturnal elastic compression.

Conclusions:

  • Puffy hand syndrome is a rare but recognized complication of intravenous drug addiction.
  • The pathophysiology may involve lymphatic toxicity from drugs and excipients.
  • While no etiological treatment exists, symptomatic management like elastic compression can be beneficial.