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Updated: Mar 19, 2026

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats
Published on: April 15, 2016
New Approaches in Locoregional Therapies for Hepatocellular Carcinoma
Riccardo Memeo1,2, Vito de Blasi3, Zineb Cherkaoui3
1Department of Digestive Surgery, University Hospital of Strasbourg, IRCAD, Research Institute Against Cancer of the Digestive Tract, IHU-Strasbourg, Institute for Image-Guided Surgery, 1, place de l'Hôpital, 67091, Strasbourg, France. riccardo.memeo@chru-strasbourg.fr.
Purpose:
Hepatocellular carcinoma (HCC) represent actually the fifth most common cancer worldwide, with liver transplantation and hepatic resection who represent the standard of care of curative treatment. Unfortunately, not all patient could benefit of curative treatment. For such patients, locoregional or systemic therapies represent a valid option in order to achieve the best survival possible.
Methods:
A review of most interesting paper actually present in literature on locoregional treatment for nonresectable nontransplantable HCC was performed.
Results:
A detailed description on each different approach has been detailed in each chapter.
Conclusion:
In case of nontransplantable and nonresectable HCC, locoregional treatment represent a valid alternative in management of this patients.
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