Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

1.4K
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
1.4K
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

416
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
416
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

421
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
421
Tonicity in Animals01:16

Tonicity in Animals

9.2K
Tonicity describes the amount of solute in a solution. The measure of the tonicity of a solution, or the total amount of solutes dissolved in a specific amount of solution, is called its osmolarity. Three terms—hypotonic, isotonic, and hypertonic—are used to relate the osmolarity of a cell to the osmolarity of the extracellular fluid that contains the cells. In a hypotonic solution, such as tap water, the extracellular fluid has a lower concentration of solutes than the fluid inside...
9.2K
Tonicity in Animals00:59

Tonicity in Animals

128.5K
The tonicity of a solution determines if a cell gains or loses water in that solution. The tonicity depends on the permeability of the cell membrane for different solutes and the concentration of nonpenetrating solutes in the solution within and outside of the cell. If a semipermeable membrane hinders the passage of some solutes but allows water to follow its concentration gradient, water moves from the side with low osmolarity (i.e., less solute) to the side with higher osmolarity (i.e.,...
128.5K
Osmosis and Osmotic Pressure of Solutions02:40

Osmosis and Osmotic Pressure of Solutions

48.5K
A number of natural and synthetic materials exhibit selective permeation, meaning that only molecules or ions of a certain size, shape, polarity, charge, and so forth, are capable of passing through (permeating) the material. Biological cell membranes provide elegant examples of selective permeation in nature, while dialysis tubing used to remove metabolic wastes from blood is a more simplistic technological example. Regardless of how they may be fabricated, these materials are generally...
48.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intensive care under uncertainty: a qualitative study of how older patients and their relatives wish to contribute to decision-making.

European geriatric medicine·2026
Same author

International training disparities in post-ICU follow-up: An international survey of physicians' practices and perceptions.

Medicina intensiva·2026
Same author

Patient and family engagement in adult and paediatric critical care research: A scoping review.

Australian critical care : official journal of the Confederation of Australian Critical Care Nurses·2026
Same author

Survey of Intensivist Coverage and Interprofessional Team Staffing in Canadian ICUs.

Critical care medicine·2026
Same author

Prevalence, semiology and neuroimaging of movements in comatose adults at risk of death by neurologic criteria: a prospective cohort study.

Critical care (London, England)·2026
Same author

Risk of Serious Adverse Events and Death With Low-Dose Methotrexate Versus Hydroxychloroquine in Adults Receiving Dialysis.

Seminars in dialysis·2026
Same journal

Interventions to prevent or cease electronic cigarette use in children and adolescents.

The Cochrane database of systematic reviews·2026
Same journal

Drugs to improve anaemia, quality of life, and physical function in people with myelodysplastic syndromes (MDS).

The Cochrane database of systematic reviews·2026
Same journal

Interventions for smoking cessation in inpatient psychiatry settings.

The Cochrane database of systematic reviews·2026
Same journal

Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.

The Cochrane database of systematic reviews·2026
Same journal

Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.

The Cochrane database of systematic reviews·2026
Same journal

Views and experiences of weight management for people living with mobility‑limiting conditions, intellectual disabilities or severe mental illness: a qualitative evidence synthesis.

The Cochrane database of systematic reviews·2026
See all related articles

Related Experiment Video

Updated: Mar 19, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

1.6K

Hypertonic salt solution for peri-operative fluid management.

Brad Shrum1, Brian Church, Eric McArthur

  • 1General Surgery Experimental Laboratory, University Hospital London Health Sciences Centre, Department of Surgery, 339 Windermere Road, London, ON, Canada, N6A 5A5.

The Cochrane Database of Systematic Reviews
|June 9, 2016
PubMed
Summary
This summary is machine-generated.

Hypertonic salt (HS) solutions reduce intravenous fluid needs during surgery compared to isotonic salt (IS) solutions, but may temporarily increase serum sodium levels. Further research is needed to determine the impact of HS on survival and morbidity.

More Related Videos

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
16:31

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Published on: June 6, 2011

25.7K
Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
09:37

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats

Published on: August 1, 2018

15.6K

Related Experiment Videos

Last Updated: Mar 19, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

1.6K
Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
16:31

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Published on: June 6, 2011

25.7K
Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
09:37

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats

Published on: August 1, 2018

15.6K

Area of Science:

  • Anesthesiology and Perioperative Medicine
  • Nephrology and Critical Care
  • Surgical Fluid Management

Background:

  • Fluid overload during surgery increases complication risks.
  • Hypertonic salt (HS) solutions maintain intravascular volume using less fluid than isotonic salt (IS) solutions.
  • HS may lead to elevated serum sodium levels.

Purpose of the Study:

  • To evaluate the benefits and harms of using HS versus IS solutions for fluid resuscitation in surgical patients.

Main Methods:

  • Systematic review and meta-analysis of randomized clinical trials (RCTs).
  • Searched multiple databases (CENTRAL, MEDLINE, EMBASE, LILACS, CINAHL) up to April 2016.
  • Assessed outcomes including mortality, organ failure, fluid balance, and serum electrolytes.

Main Results:

  • Included 18 RCTs with 1087 participants; HS required significantly less fluid volume (1.49 L vs 2.4 L).
  • HS resulted in significantly less postoperative fluid excess (2.5 L vs 4.4 L).
  • HS significantly increased maximum serum sodium levels (MD 7.73 meq/L), though generally within normal limits.

Conclusions:

  • HS effectively reduces intravenous fluid requirements in surgical patients.
  • HS causes a transient increase in serum sodium.
  • The impact of HS on surgical patient survival and morbidity requires further investigation in adequately powered RCTs.