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Related Concept Videos

Menopause01:28

Menopause

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Cognition plays a pivotal role in shaping emotional experiences, as demonstrated by Schachter and Singer’s two-factor theory of emotion. According to this model, emotion arises from a combination of physiological arousal and cognitive interpretation. The body’s physiological response to stimuli is ambiguous and only gains emotional significance through cognitive labeling. For instance, an increased heart rate and adrenaline surge while standing near an attractive person may be...
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Hormonal Regulation of the Menstrual Cycle01:22

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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
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During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
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A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...
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Related Experiment Video

Updated: Mar 19, 2026

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
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Cognition and the menopause transition.

Pauline M Maki1, Victor W Henderson

  • 11University of Illinois at Chicago College of Medicine and College of Liberal Arts and Sciences, Chicago, IL 2Stanford University, Stanford, CA.

Menopause (New York, N.Y.)
|June 9, 2016
PubMed
Summary

Menopausal transition commonly causes cognitive complaints like forgetfulness and brain fog in women. Research suggests these issues are often normal and not indicative of serious cognitive disorders like Alzheimer disease.

Area of Science:

  • Women's Health
  • Neuroscience
  • Endocrinology

Background:

  • Cognitive complaints including forgetfulness and "brain fog" are frequently reported by women during menopause.
  • Concerns arise regarding whether these symptoms are normal menopausal changes or indicative of serious neurological conditions such as Alzheimer disease.

Purpose of the Study:

  • To summarize the scientific literature on cognitive complaints in midlife women.
  • To evaluate the validity of these complaints against standardized cognitive tests.
  • To examine the impact of menopause on cognitive performance and provide recommendations.

Main Methods:

  • Literature review of studies on cognitive complaints in midlife women.
  • Analysis of the relationship between subjective cognitive complaints and objective performance on cognitive tests.

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  • Synthesis of findings on menopause's influence on cognition.
  • Main Results:

    • Cognitive complaints are common in women during the menopausal transition.
    • Subjective complaints often do not correlate with objective deficits on standardized cognitive tests.
    • Menopause can influence cognitive performance, but complaints are not typically predictive of Alzheimer disease.

    Conclusions:

    • Cognitive changes during menopause are common and often do not signify underlying pathology.
    • Healthcare providers should reassure women that these symptoms are usually related to menopause.
    • Recommendations are provided for managing cognitive concerns in midlife women.