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Updated: Mar 19, 2026
Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice
Published on: June 29, 2018
Age-related oscillatory theta modulation of multisensory integration in frontocentral regions
Tianyi Yan1, Xiaoshan Bi, Mengmeng Zhang
1aSchool of Life Science, Beijing Institute of Technology bSchool of Mechatronics Engineering, Beijing Institute of Technology cThe High School Affiliated to Renmin University of China, Beijing, China dGraduate School of Natural Science and Technology, Okayama University, Okayama, Japan.
Abstract:
This study used electroencephalogram measurements to investigate the effects of aging on oscillatory theta modulation during an audiovisual discrimination task. By a wavelet-based time-frequency analysis, age-related theta oscillation response differences were observed within a relatively restricted time range (0-500 ms) over frontal-central regions. Older adults showed stronger theta spectral power during visual and audiovisual stimuli in the left frontal regions; however, young adults showed stronger theta spectral power during auditory and audiovisual stimuli in the central regions. These findings suggest that multisensory oscillatory theta responses differ according to age, which further proves that the left frontal regions play an important role in audiovisual integration.
