Stewart-Bluefarb syndrome revisited.

Area of Science:

• Vascular Malformations
• Dermatology
• Rare Diseases

Background:

• Stewart-Bluefarb syndrome (SBS) is a rare subtype of pseudo-Kaposi sarcoma (PKS).
• PKS is associated with congenital arteriovenous malformations.
• SBS is characterized by cutaneous lesions typically appearing in the second decade of life.

Observation:

• A 33-year-old man presented with a 15-year history of unilateral, reddish-brown, raised lesions.
• Lesions were located on his right lower leg and the dorsum of his foot.
• Clinical presentation consistent with Stewart-Bluefarb syndrome.

Findings:

• Diagnosis of pseudo-Kaposi sarcoma (PKS) was confirmed via histopathology and radiology.
• The case provides detailed clinical observations of SBS.
• The study reviews the aetiopathogenesis, differential diagnosis, and treatment strategies for SBS.

Implications:

• This case contributes to the understanding of a rare vascular malformation-associated syndrome.
• Highlights the importance of accurate diagnosis and management of PKS subtypes.
• Informs clinical practice regarding the presentation and treatment of Stewart-Bluefarb syndrome.