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Updated: Mar 19, 2026

Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals
Published on: October 31, 2011
Topographical representation of odor hedonics in the olfactory bulb
Florence Kermen1,2, Maëllie Midroit1, Nicola Kuczewski1
1INSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Abstract:
Hedonic value is a dominant aspect of olfactory perception. Using optogenetic manipulation in freely behaving mice paired with immediate early gene mapping, we demonstrate that hedonic information is represented along the antero-posterior axis of the ventral olfactory bulb. Using this representation, we show that the degree of attractiveness of odors can be bidirectionally modulated by local manipulation of the olfactory bulb's neural networks in freely behaving mice.
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