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Dialyzing women and men: does it matter? An observational study
Ayse Serra Artan1, Fatih Kircelli2, Ercan Ok3
1Division of Nephrology, Department of Internal Medicine , Istanbul Medical Faculty , Istanbul , Turkey.
Clinical Kidney Journal
|June 9, 2016
Summary
Gender significantly impacts hemodialysis patient parameters, including age, BMI, and medication use. However, 3-year survival rates for male and female hemodialysis patients remain similar.
Area of Science:
- Nephrology
- Clinical Medicine
- Public Health
Background:
- Hemodialysis treatment application and outcomes can vary between genders.
- Understanding these sex-based differences is crucial for optimizing patient care.
Purpose of the Study:
- To compare demographic, clinical, biochemical, therapeutic, and prognostic parameters between male and female hemodialysis patients.
- To identify sex-specific factors that may influence hemodialysis outcomes.
Main Methods:
- Analysis of 1,999,648 hemodialysis sessions from 10,984 patients across 55 centers in the European Clinical Database (EuCliD)-Turkey.
- Comparison of incident and prevalent patient cohorts, examining various clinical and biochemical markers.
Main Results:
- Female patients were older and had higher BMIs but lower hemoglobin levels, interdialytic weight gain, and arteriovenous fistula usage.
- Medication use (erythropoiesis-stimulating agents, vitamin D) was higher in females, while hospitalization was more frequent in prevalent female patients.
- Despite significant parameter differences, no significant difference in 3-year survival rates was observed between genders.
Conclusions:
- Numerous parameters in hemodialysis patients show significant sex-based differences.
- Incorporating sex-specific considerations into treatment strategies may enhance patient outcomes.
- Further research into sex-based variations in hemodialysis is warranted for personalized medicine.
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