Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revealing Hidden Dynamics of Hydrogel-Based Desalination with <sup>23</sup>Na Nuclear Magnetic Resonance.

The journal of physical chemistry. C, Nanomaterials and interfaces·2026
Same author

Enhancing Interfacial Charge Transport in Gold Nanoparticle@Polyaniline Hybrids via N-Heterocyclic Carbene Linkers.

Angewandte Chemie (International ed. in English)·2026
Same author

Efficient and reversible chirality induction between protein and achiral plasmonic assemblies.

Nature materials·2026
Same author

Mechanically interlocked monolayer and bilayer two-dimensional polymers with high elastic modulus.

Nature synthesis·2026
Same author

Tracer Diffusivity in Amphiphilic Polymer Model Co-Networks.

Macromolecules·2026
Same author

Metal Ion-Specific Modulation of Network Connectivity and Defects in Poly(ethylene glycol)-Peptide Conjugate Assemblies and Hydrogels.

Chemistry of materials : a publication of the American Chemical Society·2026
Same journal

Synergistic Buried Interface Engineering via Ion Exchange and Passivation for High-Performance Inverted Perovskite Solar Cells.

ACS applied materials & interfaces·2026
Same journal

In Situ Wet Coating of Ammonium Phosphomolybdate for Enhancing the Kinetics and Cycling Stability of NaNi<sub>1/3</sub>Fe<sub>1/3</sub>Mn<sub>1/3</sub>O<sub>2</sub> Cathode Material.

ACS applied materials & interfaces·2026
Same journal

Molecular Hybrids of Serum Albumin and Cobalt Phthalocyanine for Asymmetric Oxidation of C=C and C-H Bonds.

ACS applied materials & interfaces·2026
Same journal

A High-Throughput Platform for Measuring and Predicting Vitrification Behavior in Multicomponent Aqueous Solutions.

ACS applied materials & interfaces·2026
Same journal

A Brain-Targeted DNA Delivery Nanocarrier Modulator for Synergistic Therapy of Parkinson's Disease.

ACS applied materials & interfaces·2026
Same journal

Quasi-Discrete Channels of Porous Coordination Polymers for Selective Multiscenario CO<sub>2</sub> Recognition.

ACS applied materials & interfaces·2026
See all related articles

Related Experiment Video

Updated: Mar 19, 2026

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

8.6K

Core-Shell Microgels with Switchable Elasticity at Constant Interfacial Interaction.

Maximilian Seuss1, Willi Schmolke2, Astrid Drechsler1

  • 1Leibniz-Institut für Polymerforschung Dresden e.V. , Institute of Physical Chemistry and Polymer Physics, Hohe Str. 6, D-01069 Dresden, Germany.

ACS Applied Materials & Interfaces
|June 9, 2016
PubMed
Summary
This summary is machine-generated.

Researchers developed novel core-shell microgels with tunable mechanics. These poly(N-isopropylacrylamide) (pNIPAAm) core and polyacrylamide (pAAm) shell particles offer independent control over material properties for advanced soft material assembly.

Keywords:
AFMcore−shell microgelselasticityinterfacial interactionthermoresponsivity

More Related Videos

Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces
08:05

Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces

Published on: September 9, 2022

3.0K
Simple Polyacrylamide-based Multiwell Stiffness Assay for the Study of Stiffness-dependent Cell Responses
07:45

Simple Polyacrylamide-based Multiwell Stiffness Assay for the Study of Stiffness-dependent Cell Responses

Published on: March 25, 2015

20.9K

Related Experiment Videos

Last Updated: Mar 19, 2026

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

8.6K
Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces
08:05

Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces

Published on: September 9, 2022

3.0K
Simple Polyacrylamide-based Multiwell Stiffness Assay for the Study of Stiffness-dependent Cell Responses
07:45

Simple Polyacrylamide-based Multiwell Stiffness Assay for the Study of Stiffness-dependent Cell Responses

Published on: March 25, 2015

20.9K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Soft Matter Physics

Background:

  • Poly(N-isopropylacrylamide) (pNIPAAm) hydrogels exhibit thermo-reversible volume phase transitions.
  • Volume changes in hydrogels affect their mechanical properties and interfacial interactions.
  • Decoupling these parameters is crucial for designing advanced soft materials.

Purpose of the Study:

  • To create submillimeter-sized hydrogel particles with independently tunable mechanics.
  • To investigate the role of a non-thermosensitive shell in modulating the thermo-responsive core behavior.
  • To develop a platform for assembling soft materials with precisely controlled properties.

Main Methods:

  • Utilizing droplet-based microfluidics to template core-shell hydrogel particles.
  • Synthesizing particles with a thermosensitive pNIPAAm core and a non-thermosensitive pAAm shell.
  • Analyzing the mechanical response and interfacial properties during thermal transitions.

Main Results:

  • The pNIPAAm core undergoes deswelling above 34 °C, leading to shell stretching.
  • The surficial Young's modulus of the microgel increases as the core deswells.
  • The pAAm shell's surface interactions remain largely temperature-independent, decoupling them from core volume changes.

Conclusions:

  • Core-shell microgels provide a platform for independent tuning of mechanics and interfacial properties.
  • These particles enable the rational assembly of soft materials with predictable and controllable characteristics.
  • The developed microgels are promising building blocks for advanced functional soft materials.