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Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
Published on: February 3, 2014
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Right ventricular outflow tract systolic excursion: a useful method for determining right ventricular systolic
Farhood Alsoos1, Mohammad Almobarak2, Hussam Shebli2
1Department of Internal Medicine, Faculty of Medicine, Damascus University, Fayez Mansour Street, Mazzeh, Damascus, Syria. fsoossoos@gmail.com.
Journal of Echocardiography
|June 10, 2016
Summary
Right ventricular outflow tract systolic excursion (RVOT_SE) is a new, accurate method for assessing right ventricular (RV) systolic function. It strongly correlates with established measures like FAC and TAPSE, showing high sensitivity and specificity.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Imaging
Background:
- Assessing right ventricular (RV) systolic function is challenging.
- Existing methods like RV fractional area change (FAC) and tricuspid annular plane systolic excursion (TAPSE) have limitations.
- Right ventricular outflow tract systolic excursion (RVOT_SE) offers a novel approach to RV function evaluation.
Purpose of the Study:
- To evaluate the correlation between the novel RVOT_SE method and established RV systolic function assessment techniques.
- To determine the diagnostic accuracy of RVOT_SE in identifying reduced RV systolic function.
Main Methods:
- RVOT_SE was defined as the systolic excursion of the RV outflow tract anterior wall endocardium.
- 104 patients with diverse RV function, ejection fraction, and pulmonary artery systolic pressure were studied.
- Measurements included RVOT_SE, FAC, TAPSE, RV outflow tract fractional shortening (RVOT_FS), and tricuspid annular systolic excursion velocity S' (Tissue S').
Main Results:
- RVOT_SE demonstrated strong correlations with RVOT_FS, FAC, and TAPSE.
- Multivariate analysis identified RVOT_FS, FAC, and TAPSE as independent predictors of RVOT_SE.
- RVOT_SE achieved 98% sensitivity and 96% specificity for diagnosing reduced RV systolic function.
- No significant correlation was found between RVOT_SE and ejection fraction or pulmonary artery systolic pressure in patients with reduced RV function.
- Favorable intra-observer and inter-observer reproducibility were reported for RVOT_SE.
Conclusions:
- RVOT_SE is a simple, accurate, and promising new method for evaluating RV systolic function.
- Its high diagnostic accuracy and reproducibility support its clinical utility.
- RVOT_SE may serve as a valuable tool in the echocardiographic assessment of RV performance.

