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Updated: Mar 19, 2026
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
Published on: February 3, 2014
Right ventricular outflow tract systolic excursion: a useful method for determining right ventricular systolic
Farhood Alsoos1, Mohammad Almobarak2, Hussam Shebli2
1Department of Internal Medicine, Faculty of Medicine, Damascus University, Fayez Mansour Street, Mazzeh, Damascus, Syria. fsoossoos@gmail.com.
Background:
Assessment of right ventricular (RV) systolic function is not an easy task. Although RV fractional area change (FAC) and tricuspid annular plane systolic excursion (TAPSE) are useful in the assessment of RV function, their use can be sometimes limited. Right ventricular outflow tract systolic excursion (RVOT_SE) is a new way to evaluate RV systolic function. The aim of this study was to assess the correlation between RVOT_SE and other RV systolic function assessment methods.
Methods:
RVOT_SE was defined as the systolic excursion of the RV outflow tract anterior wall endocardium. A total of 104 patients with a wide range of RV systolic function, ejection fraction, and pulmonary artery systolic pressure were studied. We also measured another four ways to evaluate RV systolic function, FAC, TAPSE, right ventricular outflow tract fractional shortening (RVOT_FS), and tricuspid annular systolic excursion velocity S' (Tissue S').
Results:
There was a strong correlation between RVOT_SE and each one of the four studied ways to evaluate RV systolic function. Multivariate regression analysis showed that the independent variables correlated with RVOT_SE were RVOT_FS (p < 0.0001), FAC (p = 0.005) and TAPSE (p = 0.023). RVOT_SE diagnosed patients with reduced RV systolic function with 98 % sensitivity and 96 % specificity. There was no correlation between RVOT_SE and ejection fraction, or between RVOT_SE and pulmonary artery systolic pressure in patients with reduced RV systolic function. Intra-observer and inter-observer reproducibility were favorable for RVOT_SE and all four studied ways.
Conclusions:
RVOT_SE is a simple, accurate, and promising method for evaluating RV systolic function.
