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Rhegmatogenous retinal detachment following intravitreal ocriplasmin
Haifa A Madi1, Richard J Haynes2, Diana Depla3
1Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland, SR2 9HP, UK.
Summary
Rhegmatogenous retinal detachment (RRD) is a risk after ocriplasmin (OCP) injection, particularly in patients with high myopia or retinal issues. Careful eye exams are crucial before and after OCP treatment.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Pharmacology
Background:
- Intravitreal ocriplasmin (OCP) is used for symptomatic vitreomacular traction.
- Rhegmatogenous retinal detachment (RRD) is a potential complication following OCP injection.
Purpose of the Study:
- To characterize patients who developed RRD after OCP injection.
- To evaluate the outcomes of RRD in this patient cohort.
Main Methods:
- Retrospective, multi-center observational case series.
- Review of patient case notes for those diagnosed with RRD post-OCP.
Main Results:
- Eight patients developed RRD after OCP injection, with a median onset of 16 days.
- Five patients were symptomatic, three were asymptomatic at diagnosis.
- RRD surgery achieved hole closure in 5/6 macular hole cases, with visual acuity outcomes varying.
Conclusions:
- RRD is a significant risk associated with intravitreal OCP.
- Caution is advised for OCP use in patients with high myopia and peripheral retinal pathology.
- Comprehensive retinal examinations and patient education on symptom recurrence are recommended.
