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Published on: March 28, 2025
Aortic arch thrombosis in the neonate.
Yuichiro Hashida1,2, Satoshi Yasukochi3, Kiyohiro Takigiku3
1Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan. pachinet@hotmail.co.jp.
Neonatal aortic arch thrombosis (AAT) is a rare, life-threatening condition. This case highlights successful treatment with low-molecular-weight heparin, improving blood flow and reducing thrombus size in a neonate.
Area of Science:
- Neonatal cardiology
- Pediatric cardiovascular surgery
- Vascular medicine
Background:
- Aortic arch thrombosis (AAT) in neonates is a rare but critical condition.
- It can lead to fatal compromise due to thrombotic obstruction of the ascending aorta.
- Associated conditions like severe coarctation of the aorta can exacerbate outcomes.
Purpose of the Study:
- To report a case of neonatal aortic arch thrombosis.
- To describe the diagnostic and therapeutic approach.
- To emphasize the role of echocardiography in managing AAT.
Main Methods:
- Diagnosis of AAT was confirmed using echocardiography.
- Echocardiography identified a large thrombus on the transverse aortic arch obstructing cervical arteries.
- Treatment involved low-molecular-weight heparin (LMWH).
Main Results:
- LMWH therapy led to a reduction in thrombus size.
- Hemodynamics of coarctation of the aorta improved.
- Cerebral perfusion was enhanced following treatment.
Conclusions:
- Echocardiography is crucial for diagnosing neonatal AAT.
- Echocardiography effectively monitors thrombus size and regression.
- LMWH is a viable treatment option for neonatal AAT, improving outcomes.
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