Left ventricular apical aneurysm due to unrecognized sarcoidosis
Tomizo Masuno1, Kumiko Hirata2, Nozomi Wada1
1Internal Medicine, Division of Cardiovascular Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Journal of Echocardiography
|June 10, 2016
Summary
Cardiac sarcoidosis can cause left ventricular apical aneurysms. This diagnosis was confirmed by endomyocardial biopsy showing noncaseating granulomas in a patient presenting with syncope.
Area of Science:
- Cardiology
- Pathology
- Immunology
Background:
- Cardiac sarcoidosis is an inflammatory condition affecting the heart.
- Left ventricular apical aneurysms are rare and can be associated with various underlying pathologies.
- Syncope is a potential symptom of cardiac dysfunction.
Purpose of the Study:
- To report a case of cardiac sarcoidosis presenting as a left ventricular apical aneurysm.
- To highlight the importance of considering cardiac sarcoidosis in the differential diagnosis of apical aneurysms.
Main Methods:
- A 47-year-old woman presenting with syncope underwent comprehensive cardiac evaluation.
- Diagnostic procedures included electrocardiogram, echocardiogram, cardiac catheterization, coronary angiography, and endomyocardial biopsy.
- Histopathological examination of the biopsy specimen was performed.
Main Results:
- Electrocardiogram revealed complete right bundle branch block and T-wave inversion.
- Echocardiogram showed a left ventricular apical aneurysm and thrombus.
- Coronary angiography demonstrated normal coronary arteries.
- Endomyocardial biopsy revealed noncaseating granulomas with giant cells, consistent with sarcoidosis.
Conclusions:
- Cardiac sarcoidosis can manifest as a left ventricular apical aneurysm.
- This case underscores the need to include cardiac sarcoidosis in the differential diagnosis for patients with unexplained apical aneurysms.
- Early diagnosis and appropriate management are crucial for patients with cardiac sarcoidosis.
Keywords:
Cardiac sarcoidosisLeft ventricular aneurysmLeft ventricular apical thrombusNonsustained ventricular tachycardiaMore Related Videos
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