[Changes in iron metabolism in Osler-Rendu disease]

A study of the indices of iron metabolism in 29 patients with hereditary hemorrhagic telangiectasia revealed a decrease in the level of serum iron, an increase in serum latent and total iron-binding capacity values. The level of blood transferrin studied by radial immunodiffusion was elevated. The level of ferritin in the absolute majority of patients was decreased. The obtained results were indicative of the development of true iron deficiency in the body.