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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
Published on: November 15, 2013
[Not Available]
L Goffinet1, A Breton2, C Gavillot3
1Centre Interrégional de Traitement des Brûlés, site pédiatrique, Nancy, rue du Morvan, 54511 Vandoeuvre les Nancy, France.
Insights
The best surgical evidence for early pediatric hand burn management is limited, with conflicting data on excision and grafting timing. More prospective studies are needed to establish optimal treatment protocols for children with hand burns.
Area of Science:
- Pediatric Surgery
- Burn Management
- Wound Healing
Context:
- Early management of pediatric hand burns involves surgery, medical follow-up, and scar prevention.
- This review focuses on the surgical aspects of pediatric hand burn care.
- Literature search conducted on PubMed (2005-2011) and compared with textbooks.
Purpose:
- To identify the best available evidence for the surgical management of pediatric hand burns.
- To assess the current state of knowledge regarding surgical interventions for pediatric hand burns.
Summary:
- Evidence on the optimal timing for excision and grafting in pediatric hand burns is contradictory.
- Few comparative studies exist, and they suffer from significant biases.
- Expert opinions offer guidance, but robust statistical power is lacking in current research.
Impact:
- Highlights the need for more high-quality, prospective studies with long-term follow-up.
- Emphasizes the importance of including pediatric burn patients in structured research protocols.
- Aims to improve therapeutic paradigms for pediatric hand burn surgical treatment.
Abstract:
The early management of pediatric hand burns includes surgical treatment, medical follow up and prevention of abnormal scarring by splits and/or pressure garment therapy. The aim of this review was to find the best available evidence in the literature on the surgical part of this management. This review started with a search in the PubMed database for the keywords, hand AND/OR child AND/OR burn. Only the articles published between January 1(st), 2005 and January 1(st), 2011 were selected. The data were compared to French and American textbooks. Contradictory findings were reported on the timing of the excision and graft, with only two comparative studies reported, with a lot of biases. The state of the art on the initial management of hand burns in children is not totally conclusive due to the lack of statistic power in these studies, but many expert opinions help to define options for good therapeutic paradigms. It is important to include these patients in prospective protocols with both early and long-term follow-up in order to increase the amount of evidence at our disposal.

