Related Experiment Video
Updated: Mar 19, 2026

04:28
Warm Moxibustion and Scraping as a Traditional Chinese Medicine Therapy for Cervical Spondylosis Treatment
Published on: June 27, 2025
1.5K
Dose-response of spinal manipulation for cervicogenic headache: study protocol for a randomized controlled trial
Linda Hanson1, Mitchell Haas2, Gert Bronfort1
1Center for Spirituality and Healing, The University of Minnesota, 420 Delaware St SE C592, Minneapolis, MN 55455 USA.
Chiropractic & Manual Therapies
|June 10, 2016
Summary
This study investigates the optimal dose of spinal manipulation for cervicogenic headache. Findings will guide treatment for this common and costly pain condition.
Area of Science:
- Neurology
- Pain Management
- Evidence-Based Practice
Background:
- Cervicogenic headache is a common, costly pain condition often managed by chiropractors.
- Existing evidence supports spinal manipulation, but optimal treatment dosage is unknown.
- Growing concerns about conventional treatments drive interest in alternative therapies.
Purpose of the Study:
- To describe the methodology of a randomized controlled trial (RCT) evaluating spinal manipulation dose-response for chronic cervicogenic headache.
- To determine the relationship between spinal manipulation dosage and patient outcomes in adults with cervicogenic headache.
Main Methods:
- A mixed-methods, two-site, observer-blind, parallel-group RCT (NCT01530321).
- Primary outcome: patient-reported headache frequency. Secondary outcomes: intensity, disability, quality of life, neck pain, satisfaction, medication use, and healthcare costs.
- Qualitative interviews assess patient treatment expectations.
Main Results:
- This section is not available in the provided abstract.
Conclusions:
- This is the first RCT to assess the dose-response of spinal manipulation for cervicogenic headache.
- Results will provide crucial evidence for managing adult cervicogenic headaches.
- Findings may inform clinical practice guidelines and improve patient outcomes.

