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Gallbladder bleeding-related severe gastrointestinal bleeding and shock in a case with end-stage renal disease: A
1Division of Family Medicine, Cheng Ching General Hospital Department of Internal Medicine, Division of Nephrology, Taichung Veterans General Hospital Department of Life Science, Tunghai University School of Medicine, China Medical University, Taichung Department of Medicine, National Yang Ming University, Taipei, Taiwan.
Insights
Gallbladder rupture causing severe gastrointestinal bleeding is rare. This case highlights successful non-surgical treatment for gallbladder spillage-related bleeding, emphasizing rare causes of GI hemorrhage.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Radiology
Background:
- Gallbladder (GB) bleeding is an infrequent clinical presentation, typically associated with cystic artery aneurysms or GB wall rupture.
- Common signs of GB rupture include Murphy's sign and jaundice, with hemobilia being the usual manifestation of GB bleeding.
Observation:
- This report details the first documented case of severe gastrointestinal bleeding stemming from gallbladder rupture-related bleeding.
- Computed tomography revealed gallstone spillage, a contributing factor to the bleeding.
- Uremic coagulopathy exacerbated the bleeding severity in this patient.
Findings:
- Successful non-surgical management was achieved in a patient with gallbladder spillage-related rupture and bleeding, a novel therapeutic outcome.
- The case underscores the importance of considering uncommon etiologies for significant gastrointestinal bleeding.
Implications:
- Clinicians must maintain awareness of rare causes of gastrointestinal bleeding, including those originating from the gallbladder.
- Prompt embolization of the identified bleeding artery is recommended as a primary intervention.
Abstract:
Gallbladder (GB) bleeding is very rare and it is caused by cystic artery aneurysm and rupture, or GB wall rupture. For GB rupture, the typical findings are positive Murphy's sign and jaundice. GB bleeding mostly presented as hemobilia. This is the first case presented with severe GI bleeding because of GB rupture-related GB bleeding. After comparing computed tomography, one gallstone spillage was noticed. In addition to gallstones, uremic coagulopathy also worsens the bleeding condition. This is also the first case that patients with GB spillage-related rupture and bleeding were successfully treated by nonsurgical management. Clinicians should bear in mind the rare causes of GI bleeding. Embolization of the bleeding artery should be attempted as soon as possible.
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