Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

666
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
666
Tissue Transplantation01:24

Tissue Transplantation

1.2K
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
1.2K
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

718
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
718
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

462
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
462

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Caught in the crossfire: hepato-bilio-pancreatic cancer surgery in the midst of COVID-19.

The British journal of surgery·2020
Same author

Global Transplantation COVID Report March 2020.

Transplantation·2020
Same author

The rise and potential fall of pancreas transplantation.

British medical bulletin·2017
Same author

Significance of steatosis in pancreatic transplantation.

Transplantation reviews (Orlando, Fla.)·2017
Same author

The use of kinase inhibitors in solid organ transplantation.

Transplantation reviews (Orlando, Fla.)·2017
Same author

A Christmas renaissance.

BMJ (Clinical research ed.)·2016

Related Experiment Video

Updated: Mar 19, 2026

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation
10:32

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation

Published on: July 20, 2022

2.6K

Challenges in pancreas transplantation.

E J Sharples1, S M Mittal2, P J Friend3

  • 1Oxford Transplant Centre, Churchill Hospital, Oxford University Hospitals, Old Road, Headington, Oxford, OX3 7LE, UK. Edward.Sharples@ouh.nhs.uk.

Acta Diabetologica
|June 11, 2016
PubMed
Summary

Pancreas transplantation offers a definitive treatment for type 1 diabetes, restoring normal glucose levels and improving survival rates. This safe and effective procedure helps prevent long-term diabetes complications.

Keywords:
DiabetesIncretinPancreas transplant

More Related Videos

Intraportal Transplantation of Pancreatic Islets in Mouse Model
09:01

Intraportal Transplantation of Pancreatic Islets in Mouse Model

Published on: May 5, 2018

10.4K
Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
09:01

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

Published on: July 27, 2022

2.7K

Related Experiment Videos

Last Updated: Mar 19, 2026

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation
10:32

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation

Published on: July 20, 2022

2.6K
Intraportal Transplantation of Pancreatic Islets in Mouse Model
09:01

Intraportal Transplantation of Pancreatic Islets in Mouse Model

Published on: May 5, 2018

10.4K
Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
09:01

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

Published on: July 27, 2022

2.7K

Area of Science:

  • Transplantation immunology
  • Endocrinology
  • Nephrology

Background:

  • Type 1 diabetes management often involves lifelong insulin therapy.
  • Secondary complications of diabetes significantly impact patient morbidity and mortality.
  • Pancreas transplantation is a potential definitive treatment option.

Purpose of the Study:

  • To review current areas of interest in pancreas transplantation.
  • To highlight the benefits of pancreas transplantation for type 1 diabetes patients.
  • To discuss the safety and efficacy of pancreas transplantation.

Main Methods:

  • Review of recent UK data on pancreas transplantation outcomes.
  • Analysis of patient survival rates compared to waiting list and kidney transplant alone.
  • Assessment of graft survival rates at 1 and 5 years.

Main Results:

  • Pancreas transplantation restores normal glucose homeostasis and insulin independence.
  • It delays or prevents secondary diabetes complications.
  • 1-year patient survival exceeds 97%, with 1-year graft survival at 85% and 5-year graft survival at 76%.

Conclusions:

  • Pancreas transplantation is a safe and effective treatment for type 1 diabetes.
  • It improves patient survival compared to waiting list or kidney transplant alone.
  • The procedure offers significant long-term benefits for patients with diabetes.