[ECHO-II virus, the pathogen of the third outbreak of uveitis in children in Kransnoyarsk, 1986]

The third outbreak of an acute infection accompanied in 3 cases by inflammation of the uveal membrane (uveitis) was recorded among infants in Krasnoyarsk in 1986. From the infants with the eye involvement as well as from those in contact with the former, 36 strains of ECHO-11 virus were isolated, and seroconversion to this virus was demonstrated. All the infants in contact with the eye patients were given gamma-globulin which seemed to limit the spread of the infection. The third outbreak of uveitis, 1986, was similar to the 1st (1980-1981) and 2nd (1982) outbreaks of uveitis in Krasnoyarsk in such aspects as the clinical eye disease (anterior uveitis-iridocyclitis), symptoms of general infection, age of the infants (3-8 months), the nosocomial pattern of infection, enterovirus etiology, marked ophthalmotropism of ECHO-11 virus isolates in monkeys.