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Updated: Mar 19, 2026

Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity
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Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity

Published on: October 17, 2025

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Regorafenib could cause sinusoidal obstruction syndrome

Motoi Takahashi1, Shigeru Harada1, Hideo Suzuki1

  • 11 Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan ; 2 Department of Hepatology, 3 Department of Surgery, Steel Memorial Yawata Hospital, Kitakyushu, Japan.

Journal of Gastrointestinal Oncology
|June 11, 2016
PubMed

Keywords:
Sinusoidal obstruction syndrome (SOS)acute liver failuredrug-induced liver injury

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