Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hallucination at low radiation dose: Evaluation of two deep-learning reconstruction methods in high-resolution chest CT.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same author

Design of a next-generation conventional scintillator x-ray detector: Improved spatial resolution and fill factor.

Medical physics·2026
Same author

A framework for quantifying and leveraging uncertainty in pre-trained CT denoising model.

IEEE transactions on bio-medical engineering·2026
Same author

Color CT, literally.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same author

System design options for a high-resolution, conventional scintillator detector.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same author

Reading, Fast and Slow: Characterizing Radiologists' Visual Search Through Abdominal CT for Detecting Hepatic Metastases.

Academic radiology·2026
Same journal

Literature Reviews After AI.

Journal of medical imaging (Bellingham, Wash.)·2026
Same journal

Illustration of transfer learning from breast cancer detection to risk prediction: adaptation to local data and local objectives.

Journal of medical imaging (Bellingham, Wash.)·2026
Same journal

RadGazeGen: radiomics and gaze-guided chest X-ray generation using diffusion models.

Journal of medical imaging (Bellingham, Wash.)·2026
Same journal

DDARes-U<sup>2</sup>Net: a dual-decoder adversarial residual U<sup>2</sup>Net algorithm for segmentation of COVID-19 pneumonia lesions.

Journal of medical imaging (Bellingham, Wash.)·2026
Same journal

High-speed optical tracking and augmented reality platform for image-guided interventions.

Journal of medical imaging (Bellingham, Wash.)·2026
Same journal

Transplant-ready? Evaluating AI lung segmentation models in candidates with severe lung disease.

Journal of medical imaging (Bellingham, Wash.)·2026
See all related articles

Related Experiment Video

Updated: Mar 19, 2026

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source
12:19

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Published on: April 4, 2017

8.9K

Improving pulse detection in multibin photon-counting detectors.

Scott S Hsieh1, Norbert J Pelc2

  • 1Stanford University, Department of Radiology, 1201 Welch Road, Stanford, California 94305, United States; Stanford University, Department of Electrical Engineering, 350 Serra Mall, Stanford, California 94305, United States.

Journal of Medical Imaging (Bellingham, Wash.)
|June 11, 2016
PubMed
Summary
This summary is machine-generated.

New pulse detection methods for energy-discriminating, photon-counting (EDPC) detectors significantly reduce spectral imaging noise at high count rates. These advancements overcome limitations of conventional comparators, improving data accuracy.

Keywords:
comparatorsphoton-counting detectorspulse pileupspectral imaging

More Related Videos

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One &#945;-Synuclein Monomer at a Time
07:56

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time

Published on: May 30, 2021

3.6K
Measuring Diffusion Coefficients via Two-photon Fluorescence Recovery After Photobleaching
07:00

Measuring Diffusion Coefficients via Two-photon Fluorescence Recovery After Photobleaching

Published on: February 26, 2010

11.8K

Related Experiment Videos

Last Updated: Mar 19, 2026

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source
12:19

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Published on: April 4, 2017

8.9K
Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One &#945;-Synuclein Monomer at a Time
07:56

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time

Published on: May 30, 2021

3.6K
Measuring Diffusion Coefficients via Two-photon Fluorescence Recovery After Photobleaching
07:00

Measuring Diffusion Coefficients via Two-photon Fluorescence Recovery After Photobleaching

Published on: February 26, 2010

11.8K

Area of Science:

  • Medical Physics
  • Detector Technology
  • Image Processing

Background:

  • Energy-discriminating, photon-counting (EDPC) detectors offer enhanced detective quantum efficiency and spectral imaging.
  • High count rates in existing EDPC detectors lead to count loss, spectral distortion, and diminished performance.
  • Current EDPC detectors rely on comparator banks for pulse identification, limiting high count rate capabilities.

Purpose of the Study:

  • To explore alternative pulse detection methods for multibin EDPC detectors.
  • To improve EDPC detector performance under high count rate conditions.
  • To reduce stochastic noise in spectral imaging tasks.

Main Methods:

  • Simulated EDPC detector signals using Monte Carlo methods with a bipolar pulse shape.
  • Analyzed simulated signals using conventional comparator banks and novel pulse detection techniques.
  • Quantified performance by calculating the Cramer-Rao lower bound for basis material estimates.

Main Results:

  • Alternative pulse detection methods significantly reduced variance in water material measurements (bone canceled) by up to an order of magnitude at high count rates.
  • Improvements in virtual monoenergetic images were modest.
  • The Cramer-Rao lower bound analysis indicated superior performance for novel methods compared to conventional comparators.

Conclusions:

  • Alternative pulse detection strategies can mitigate count loss and spectral distortion in EDPC detectors at high count rates.
  • Utilizing advanced pulse detection methods offers a pathway to reduce stochastic noise in spectral imaging.
  • These findings suggest potential for enhanced diagnostic accuracy in applications relying on spectral imaging.