[Hypertension during pregnancy: the challenge continues]

Area of Science:

• Obstetrics and Gynecology
• Cardiovascular Medicine
• Perinatology

Background:

• Hypertensive disorders affect 5-10% of pregnancies globally.
• They are a leading cause of maternal and neonatal morbidity and mortality.
• Conditions include chronic hypertension, gestational hypertension, and preeclampsia.

Purpose of the Study:

• To review the pathophysiology and progression of hypertensive disorders in pregnancy.
• To explore therapeutic options for preeclampsia.
• To consolidate current understanding of pregnancy-induced hypertension.

Main Methods:

• Literature review focusing on pathophysiology and etiology of hypertensive disorders in pregnancy.
• Analysis of research on placental factors, immunological reactions, and maternal constitutional factors.
• Examination of therapeutic strategies for preeclampsia.

Main Results:

• Hypertensive disorders encompass chronic hypertension, gestational hypertension, and preeclampsia.
• Research often focuses on preeclampsia's etiology, exploring placental, immunological, and maternal factors.
• Pathophysiology involves cardiovascular health and endothelial dysfunction.

Conclusions:

• Understanding the continuum of hypertensive disorders in pregnancy is crucial.
• Further research into preeclampsia's etiology and effective therapeutic options is warranted.
• Comprehensive review of pathophysiology and treatment strategies is presented.