Related Experiment Video
Updated: Mar 19, 2026
08:03
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
371
The FaceBase Consortium: a comprehensive resource for craniofacial researchers
James F Brinkley1, Shannon Fisher2, Matthew P Harris3
1Structural Informatics Group, Department of Biological Structure, University of Washington, Seattle, WA 98195, USA.
Development (Cambridge, England)
|June 12, 2016
Summary
The FaceBase Consortium provides comprehensive craniofacial developmental biology data resources, including imaging and genetic studies, to advance research and improve patient health care.
Area of Science:
- Craniofacial developmental biology
- Genomics
- Bioinformatics
Background:
- The FaceBase Consortium, funded by the National Institute of Dental and Craniofacial Research (NICDR), aims to advance craniofacial developmental biology.
- Existing research requires integrated, high-throughput data resources for comprehensive analysis.
Purpose of the Study:
- To accelerate understanding of craniofacial developmental biology.
- To empower the research community with comprehensive data resources.
- To foster collaborations and translate scientific findings into improved patient health care.
Main Methods:
- Generating dynamic imaging modalities and genome-wide association studies.
- Developing software tools for analyzing human facial abnormalities and detailed phenotyping.
- Creating anatomical and molecular atlases, gene expression patterns, and transcriptional profiling.
Main Results:
- Integrated data visualization tools, faceted search, and curation provided by the FaceBase Hub.
- Flexible and intuitive interaction with multidisciplinary craniofacial data.
- Datasets offer opportunities for new collaborations and training in craniofacial studies.
Conclusions:
- The FaceBase Consortium successfully integrates diverse datasets to facilitate craniofacial research.
- The provided resources empower researchers with advanced tools and data for hypothesis-driven studies.
- This initiative supports the translation of scientific discoveries into improved craniofacial health outcomes.
More Related Videos
10:23Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
3.9K
05:49Author Spotlight: Advancing CBCT and Digital Dental Image Integration with AI-Assisted Digitization
Published on: February 23, 2024
1.6K
Related Concept Videos
01:14Cranial Bones: Superior and Posterior View
8.5K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
8.5K
01:27Cranial Bones: Lateral View
7.8K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
7.8K
01:08Overview of the Skull
8.8K
The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
8.8K
01:14Muscles for Facial Expressions
5.5K
The craniofacial muscles are a collection of approximately 20 thin skeletal muscles situated beneath the skin of the face and scalp. These muscles, primarily responsible for the vast array of human facial expressions, originate from the bones or fibrous structures of the skull and extend outwards to connect with the skin. While most skeletal muscles in the body are enveloped in thick fascia, facial muscles generally have a more delicate fascial covering, with the buccinator muscle being a...
5.5K
01:21Association Areas of the Cortex
10.3K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
10.3K
01:22Sutures of the Skull
14.0K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
14.0K