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Simultaneous bilateral primary choroidal melanoma.

N Eide1

  • 1Department of Ophthalmology, Rikshospitale, University of Oslo, Norway.

Acta Ophthalmologica
|April 1, 1989
PubMed
Summary
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This case study reports Norway's first instance of primary bilateral choroidal melanoma in a 73-year-old woman. Treatment with radiation therapy led to tumor regression and improved vision, though metastasis ultimately proved fatal.

Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Primary bilateral malignant melanoma of the choroid is a rare condition.
  • This report details the first documented case in Norway.

Observation:

  • A 73-year-old woman presented with choroidal melanoma in her left eye.
  • An asymptomatic tumor was incidentally found in her right eye.
  • The left eye was enucleated, confirming a mixed-type choroidal melanoma.

Findings:

  • The asymptomatic right eye tumor exhibited significant growth after 3.5 years.
  • Rapid growth led to vitreous hemorrhage and secondary retinal detachment.
  • External radiation (33.6 Gy) achieved tumor regression, improved visual acuity to 0.5, and retinal re-attachment.

Implications:

Related Experiment Videos

  • External beam radiation therapy can be an effective treatment for bilateral choroidal melanoma.
  • Early detection and prompt intervention are crucial for managing rare ocular cancers.
  • Despite successful local treatment, systemic metastasis remains a significant challenge in choroidal melanoma management.