Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise Stress Test01:26

Exercise Stress Test

1.8K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.8K
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

660
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
660
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

4.4K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
4.4K
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

727
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
727
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

799
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
799
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

4.9K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical course and outcomes of antibody-mediated rejection after heart transplant in the contemporary era.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Exercise Performance With Aficamten vs Metoprolol in Obstructive Hypertrophic Cardiomyopathy: The MAPLE-HCM Randomized Clinical Trial.

JAMA cardiology·2026
Same author

Palliative Care in Advanced Heart Failure.

Current heart failure reports·2026
Same author

Impact of D-type personality and depressive symptoms on functional status and quality of life in worsening heart failure.

European journal of cardiovascular nursing·2026
Same author

The comeback of digitalis (digitoxin): the DIGIT-HF trial.

European heart journal supplements : journal of the European Society of Cardiology·2026
Same author

Unexpected therapeutic scenarios: initiating SGLT2 inhibitors in de novo heart failure without echocardiography.

European heart journal supplements : journal of the European Society of Cardiology·2026

Related Experiment Video

Updated: Mar 19, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.3K

Cardiopulmonary Exercise Testing in Heart Failure.

Rajeev Malhotra1, Kristian Bakken2, Emilia D'Elia3

  • 1Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

JACC. Heart Failure
|June 13, 2016
PubMed
Summary
This summary is machine-generated.

Cardiopulmonary exercise testing (CPET) precisely measures exercise capacity in heart failure (HF) patients. CPET data, including peak oxygen uptake (VO2), guides advanced HF interventions and predicts prognosis.

Keywords:
cardiopulmonary exercise testingexercise physiologyheart failureoxygen uptakeventilatory efficiency

More Related Videos

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
07:10

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

10.6K
Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects
06:57

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Published on: February 12, 2021

3.7K

Related Experiment Videos

Last Updated: Mar 19, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.3K
Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
07:10

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

10.6K
Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects
06:57

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Published on: February 12, 2021

3.7K

Area of Science:

  • Cardiology
  • Pulmonology
  • Exercise Physiology

Background:

  • Exercise intolerance, marked by dyspnea and fatigue, is a key symptom of heart failure (HF).
  • Cardiopulmonary exercise testing (CPET) is crucial for assessing exercise capacity in HF.
  • Peak oxygen uptake (VO2) measured by CPET is vital for selecting patients for advanced HF therapies.

Purpose of the Study:

  • To review the clinical and research applications of CPET in heart failure patients.
  • To discuss the interpretation of gas exchange patterns in HF across disease spectrum.
  • To highlight the prognostic value of CPET variables in HF management.

Main Methods:

  • CPET precisely measures peak oxygen uptake (VO2) to define maximum exercise capacity.
  • Submaximal CPET variables offer insights into daily living activities and prognosis.
  • Integration of CPET with hemodynamic monitoring and cardiac imaging provides comprehensive assessment.

Main Results:

  • Peak VO2 values are critical for guiding heart transplantation and ventricular assist device selection.
  • Submaximal CPET data are valuable for assessing daily activity limitations and prognosis.
  • CPET variables are reproducible and accurately reflect HF severity, endorsed by scientific statements.

Conclusions:

  • CPET is an essential tool for evaluating exercise capacity and prognosis in heart failure.
  • CPET findings inform clinical decisions regarding advanced HF interventions.
  • Understanding CPET gas exchange patterns aids in managing HF patients from preclinical to advanced stages.