[Study of renal function after the administration of a low-osmolarity iodized contrast medium. Prospective study]

We analysed the development of various kidney function parameters in 40 patients on whom an intravenous urography had been carried out with a non-ionic contrast medium of low osmolarity (iohexol). No patient displayed prior renal insufficiency (serum creatinine 0.4-2mg/dl). Twenty-four hours after injection of the iodized contrast no significant variations in urea blood concentrations, creatinine, sodium or uric acid appeared. As a result of the urography an increase in urine osmolarity and a decrease in fractional sodium excretion took place.

in patients without renal insufficiency intravenous urography with iohexol does not give rise to a significant alteration in the renal excretory function.