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Updated: Mar 19, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Endoscopic endonasal resection of ACTH secreting pituitary microadenoma; how I do it
Marina L Reppucci1, Amir R Dehdashti2
1Department of Neurosurgery, Cushing Neuroscience Institute, North Shore University Hospital, 300 Community Drive, Manhasset, NY, 11030, USA.
Background:
Transsphenoidal selective adenectomy is considered the treatment of choice in patients with Cushing's disease given the possibility for high remission and low complication rates. The endoscopic endonasal surgical nuances for Cushing's disease are not well illustrated in the neurosurgical technique and video collections.
Methods:
We describe the technical nuances of microadenoma resection for two cases of Cushing's disease, one in which the adenoma is visualized on imaging and one in which the pre-operative MRI is negative.
Conclusions:
Transsphenoidal endoscopic selective adenectomy is a safe and effective surgery for patients with Cushing's disease regardless of preoperative MRI findings.
