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Related Experiment Videos

Nonobstructive dysphagia in reflux esophagitis.

G Triadafilopoulos1

  • 1Evans Memorial Department of Clinical Research, University Hospital, Boston, Massachusetts.

The American Journal of Gastroenterology
|June 1, 1989
PubMed
Summary
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Nonobstructive dysphagia (NOD) is common in reflux esophagitis patients. Acid reflux frequently triggers this swallowing difficulty in esophagitis, but not in motility disorder patients.

Area of Science:

  • Gastroenterology
  • Esophageal Physiology

Background:

  • Dysphagia can occur without esophageal stricture, particularly in reflux esophagitis.
  • This
  • nonobstructive dysphagia
  • (NOD) is thought to stem from transient esophageal motor issues.

Purpose of the Study:

  • To assess the frequency of NOD in reflux esophagitis patients.
  • To correlate NOD with esophageal pH and motility changes.

Main Methods:

  • Sixty-three patients with esophageal dysfunction symptoms underwent endoscopy, esophageal manometry, and 24-hour ambulatory esophageal pH monitoring.
  • Patients included those with severe erosive esophagitis and controls with esophageal motility disorders.

Main Results:

Related Experiment Videos

  • Twenty-eight of 63 patients experienced NOD; 22 had esophagitis and 6 had esophageal dysmotility.
  • NOD occurred in 46.8% of esophagitis patients and 37.5% of controls.
  • NOD correlated with esophageal pH < 4.0 in 88.6% of esophagitis patients, but only 7% of controls (p < 0.001).
  • No correlation was found between NOD and baseline esophageal motility abnormalities.

Conclusions:

  • Nonobstructive dysphagia is a frequent, intermittent symptom in esophagitis patients.
  • Esophageal acid exposure is a likely trigger for dysphagia in esophagitis, unlike in motility disorders.