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Spinal Cord: Gross Anatomy01:15

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Related Experiment Video

Updated: Mar 19, 2026

Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
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Spinal Cord Schistosomiasis: Two Different Outcomes.

Mohammed Alsomaili1, Ahmad A Abulaban1

  • 1Department of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.

Case Reports in Neurology
|June 14, 2016
PubMed
Summary

Early diagnosis and praziquantel treatment are key for spinal cord schistosomiasis recovery. Prompt intervention in these myelopathy cases significantly improves patient outcomes, unlike delayed treatment.

Keywords:
MyelopathySaudi ArabiaSpinal cord schistosomiasis

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Parasitology

Background:

  • Spinal cord schistosomiasis diagnosis is challenging in non-endemic regions.
  • Myelopathy presentation requires careful consideration of parasitic infections.

Observation:

  • Two young Saudi males presented with myelopathy due to spinal cord schistosomiasis.
  • Case 1: Late presentation (3 months), received steroids and plasma exchange, praziquantel administered late, no recovery.
  • Case 2: Early presentation (8 weeks), received praziquantel only, complete recovery.

Findings:

  • Early recognition and treatment with praziquantel are critical for favorable outcomes.
  • Prompt praziquantel administration in early-stage myelopathy led to full recovery.
  • Delayed treatment and adjunctive therapies (steroids, plasma exchange) did not prevent poor outcomes.

Implications:

  • Highlights the importance of considering spinal cord schistosomiasis in myelopathy patients, especially in or returning from endemic areas.
  • Suggests praziquantel as the primary treatment, emphasizing timely administration.
  • Further research is needed to clarify the role of steroid therapy in spinal cord schistosomiasis.