Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

6.4K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
6.4K
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

603
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
603
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

1.2K
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discrete foraging landscapes support large scale migrations of a marine fish.

Movement ecology·2026
Same author

Bioaccumulation of trace elements by Leach's storm-petrels (Hydrobates leucorhous) in the North and South Atlantic Ocean during the non-breeding period.

Marine pollution bulletin·2026
Same author

Challenging 10 misconceptions in conservation physiology.

Conservation physiology·2026
Same author

Tips and tricks for addressing and responding to peer reviews.

Conservation physiology·2026
Same author

The evidence base for ranger patrol effectiveness in conservation and how to improve it.

Biological reviews of the Cambridge Philosophical Society·2026
Same author

Fish welfare in a changing world: New developments and current challenges.

Journal of fish biology·2026

Related Experiment Video

Updated: Mar 19, 2026

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

10.2K

Manipulating glucocorticoids in wild animals: basic and applied perspectives.

Natalie M Sopinka1, Lucy D Patterson2, Julia C Redfern2

  • 1Department of Forest and Conservation Sciences, University of British Columbia, Vancouver, BC, Canada V6T 1Z4; Fish Ecology and Conservation Physiology Laboratory, Department of Biology, Carleton University, Ottawa, ON, Canada K1S 5B6.

Conservation Physiology
|June 14, 2016
PubMed
Summary

Experimental glucocorticoid (GC) manipulation in wild animals reveals diverse effects on survival and reproduction. Future research should validate GC changes within natural ranges to understand ecological impacts and inform conservation.

Keywords:
Corticosteronecortisolendocrinologyhormonelife historystress

More Related Videos

Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions
04:33

Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions

Published on: March 12, 2019

8.6K
Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice
09:37

Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice

Published on: August 13, 2020

12.3K

Related Experiment Videos

Last Updated: Mar 19, 2026

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

10.2K
Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions
04:33

Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions

Published on: March 12, 2019

8.6K
Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice
09:37

Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice

Published on: August 13, 2020

12.3K

Area of Science:

  • Ecology
  • Evolutionary Biology
  • Physiology

Background:

  • Glucocorticoids (GCs) are key stress response hormones in vertebrates.
  • Laboratory studies on GCs provide mechanistic insights but lack ecological relevance.
  • Understanding GC effects in wild populations is crucial for ecological and evolutionary research.

Purpose of the Study:

  • To review emerging research on experimental glucocorticoid (GC) manipulation in wild vertebrates.
  • To assess GC-mediated effects on survival, physiology, behavior, reproduction, and offspring quality.
  • To explore the implications of GC manipulation studies for animal conservation and understanding population dynamics.

Main Methods:

  • Review of studies involving exogenous manipulation of GCs in wild vertebrates.
  • Analysis of reported effects of GC manipulation on various fitness and life-history traits.
  • Synthesis of factors contributing to the diversity of responses observed across studies.

Main Results:

  • Exogenous GC manipulation yielded varied effects (increases, decreases, or no change) on traits across taxa.
  • Response diversity is linked to experimental methods, species-specific traits, and ecological context.
  • Existing experimental data can inform conservation on a case-by-case basis.

Conclusions:

  • Experimental GC manipulation is a promising tool for understanding fitness impairment and population declines.
  • Integrating mechanistic insights with functional conservation applications is essential.
  • Future research needs to consider multiple traits, individual variation, and physiologically relevant GC ranges.