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Smart Thin Hydrogel Coatings Harnessing Hydrophobicity and Topography to Capture and Release Cancer Cells
Luying Wang1,2, Hongliang Liu3, Feilong Zhang1,2
1Beijing National Laboratory for MolecularSciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Abstract:
Smart thin hydrogel coatings are fabricated to capture and release targeted cancer cells by simultaneously tuning surface hydrophobicity and topography. At physiological temperature, the targeted cancer cells are captured on the hydrophobic and wrinkled coating surface. At room temperature, the captured cells are released from the hydrophilic and smooth coating surface.
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