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Prevalence and Clinical Features of Focal Takotsubo Cardiomyopathy

Ken Kato1, Hideki Kitahara, Yoshihide Fujimoto

  • 1Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine.

Circulation Journal : Official Journal of the Japanese Circulation Society
|June 15, 2016
PubMed

Insights

Focal takotsubo cardiomyopathy is not rare, with 10 cases identified. Biplane left ventriculography aids in diagnosing this condition, which presents differently from other takotsubo cardiomyopathy types.

Area of Science:

  • Cardiology
  • Cardiovascular Diseases
  • Medical Diagnostics

Background:

  • Distinguishing focal takotsubo cardiomyopathy from myocardial infarction is challenging.
  • Limited data exists on the prevalence and clinical characteristics of focal takotsubo cardiomyopathy.

Purpose of the Study:

  • To determine the prevalence and clinical features of focal takotsubo cardiomyopathy.
  • To compare focal takotsubo cardiomyopathy with other takotsubo cardiomyopathy variants.

Main Methods:

  • Cardiac catheterization databases were queried for patients with focal takotsubo cardiomyopathy.
  • Focal takotsubo cardiomyopathy defined by specific wall motion abnormalities without obstructive coronary artery disease.
  • Comparison of clinical features and in-hospital outcomes between focal and other takotsubo cardiomyopathy types.

Main Results:

  • 10 patients (6.9%) were diagnosed with focal takotsubo cardiomyopathy among 144 total takotsubo cardiomyopathy cases.
  • Focal takotsubo cardiomyopathy showed a significantly higher left ventricular ejection fraction compared to apical and mid-ventricular types (56±13% vs. 45±13% vs. 46±12%, P=0.03).
  • No significant difference in in-hospital outcomes was observed among the different takotsubo cardiomyopathy types.

Conclusions:

  • Focal takotsubo cardiomyopathy is a relatively common condition.
  • Biplane left ventriculography is an effective diagnostic tool for focal takotsubo cardiomyopathy.
Abstract

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