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New toothpaste to deal with dentine hypersensitivity: double-blind randomized controlled clinical trial
T Katanec1, M Majstorovic2,3, D Negovetic Vranic4
1School of Dental Medicine, Pediatric Dentistry, University of Zagreb, University Clinical Hospital Center Zagreb, Zagreb, Croatia, Europe.
International Journal of Dental Hygiene
|June 15, 2016
Summary
This study found that a new toothpaste containing potassium nitrate and zinc citrate effectively reduced dentine hypersensitivity. Significant pain reduction was observed after four weeks of regular use.
Area of Science:
- Dentistry
- Oral Health
- Biomaterials
Background:
- Dentine hypersensitivity is a common dental condition causing sharp pain.
- Effective management strategies are crucial for improving patient quality of life.
Purpose of the Study:
- To evaluate the efficacy of a novel toothpaste formulation in alleviating dentine hypersensitivity.
- To assess the combined effect of potassium nitrate and zinc citrate.
Main Methods:
- A clinical study was conducted using a toothpaste with 5.00% potassium nitrate and 0.50% zinc citrate.
- Pain perception to thermal (water) and air stimuli was measured using the Visual Analogue Scale (VAS).
- Dental history of participants was recorded.
Main Results:
- The tested toothpaste demonstrated a significant reduction in dentine hypersensitivity, with 40% reduction after 4 weeks.
- A statistically significant difference in pain reduction was noted for both water and air stimuli after 4 weeks (P = 0.033, P = 0.006).
- Control groups showed a less pronounced reduction in sensitivity.
Conclusions:
- The tested toothpaste formulation is effective in reducing dentine hypersensitivity.
- Four weeks of regular use can lead to significant relief from tooth sensitivity.
