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Salmonella Persistence within the Peripheral Lymph Nodes of Cattle following Experimental Inoculation
T S Edrington1, G H Loneragan2, K J Genovese3
1U.S. Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, 2881 F&B Road, College Station, Texas 77845, USA. tom.edrington@ars.usda.gov.
Journal of Food Protection
|June 15, 2016
Summary
Salmonella infection in steer lymph nodes persisted for at least 21 days post-inoculation. Complete Salmonella clearance in cattle was estimated to occur around 28 days, requiring further research for verification.
Area of Science:
- Veterinary Microbiology
- Animal Health
- Bacteriology
Background:
- Salmonella infections pose a significant threat to cattle health and food safety.
- Understanding the duration and clearance of Salmonella in host tissues is crucial for effective disease management.
Purpose of the Study:
- To determine the duration of Salmonella infection in peripheral lymph nodes of steers following transdermal inoculation.
- To investigate the clearance kinetics of Salmonella Montevideo in bovine lymph nodes.
Main Methods:
- Thirty-six Holstein steers were transdermally inoculated with Salmonella Montevideo.
- Lymph nodes were collected at various time points (6 hours to 28 days) post-inoculation.
- Quantitative and qualitative cultures were performed to detect and quantify Salmonella.
Main Results:
- Salmonella was detected in lymph nodes from 6 hours up to 21 days post-inoculation.
- Salmonella levels ranged from 0.8 to 1.8 log CFU/g in infected lymph nodes.
- Elimination of Salmonella appeared to commence around day 14, with potential clearance by day 28.
Conclusions:
- Salmonella can persist in steer peripheral lymph nodes for at least 21 days after inoculation.
- Complete clearance of Salmonella in cattle may require up to 28 days.
- Further studies with extended necropsy times are needed to confirm complete Salmonella elimination.
