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Blood Lead Levels in Young Children: US, 2009-2015
Leland F McClure1, Justin K Niles1, Harvey W Kaufman1
1Quest Diagnostics, Madison, NJ.
Insights
Blood lead levels in children under 6 generally declined over time, but 3.0% still showed high levels (≥5.0 μg/dL). Factors like housing age and poverty income ratio significantly impacted these elevated blood lead levels.
Area of Science:
- Environmental Health
- Pediatric Health
- Public Health Surveillance
Background:
- Childhood lead exposure remains a significant public health concern.
- Previous data from the National Health and Nutrition Examination Survey (NHANES) provided limited scope for detailed analysis.
- A larger dataset is crucial for understanding trends and disparities in blood lead levels.
Purpose of the Study:
- To evaluate trends in blood lead levels (BLLs) among children under 6 years of age.
- To provide a more detailed and novel assessment of BLLs using a significantly larger dataset than NHANES.
- To identify demographic and geographic factors associated with elevated BLLs.
Main Methods:
- Retrospective analysis of over 5 million blood lead level results from May 2009 to April 2015.
- Inclusion of over 3.8 million venous blood lead level results from children under 6 years old across all 50 states and D.C.
- Evaluation of yearly changes and analysis by sex, housing age, poverty income ratio (PIR), Medicaid status, and geographic regions.
Main Results:
- 3.0% of children under 6 years had blood lead levels ≥5.0 μg/dL (high BLLs).
- Significant disparities in high BLLs were observed based on sex, pre-1950s housing construction, and PIR (<1.25 and >5).
- Marked geographic variations in high BLLs and very high BLLs (≥10.0 μg/dL) were noted, though overall levels generally declined over time.
Conclusions:
- Analysis of over 5 million venous BLLs provided robust insights into geographic and demographic disparities.
- Progress in reducing childhood lead toxicity is evident, but challenges persist.
- Specific factors identified continue to pose significant risks, necessitating ongoing public health interventions.
Objectives:
To evaluate trends in blood lead levels in children <6 years of age, this Quest Diagnostics Health Trends report builds on previously reported National Health and Nutrition Examination Survey data with a much larger national group and adds more detail and novel assessments.
Study Design:
This report describes the results from a 6-year retrospective study (May 2009-April 2015) based on >5 million blood lead level results (including >3.8 million venous results) from children <6 years old living in all 50 states and the District of Columbia. We evaluated yearly changes and examined demographic categories including sex, pre-1950s housing construction, poverty income ratios (PIRs), Medicaid enrollment status, and geographic regions.
Results:
Among children <6 years old, 3.0% exhibited blood lead levels ≥5.0 μg/dL (high). There were significant differences in high blood lead levels based on sex, pre-1950s housing construction quintiles, and PIR <1.25 and PIR >5 (all P < .01). Health and Human Services regions, states, and 3-digit ZIP code areas exhibited drastically different frequencies of high blood lead levels and blood lead levels ≥10.0 μg/dL (very high). Generally, levels declined over time for all groups.
Conclusion:
Examination of more than 5 million venous blood lead level results in children younger than 6 years old allowed for a robust, detailed analysis of blood lead level group results by geography and other criteria that are prohibited with the narrower National Health and Nutrition Examination Survey database. Progress in reducing the burden of lead toxicity is a public health success story that is incomplete with some identified factors posing larger, ongoing challenges.
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