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Published on: July 24, 2013
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[Thyroid dysfunction among HIV infected patients].
Summary
Thyroid dysfunction is common in human immunodeficiency virus (HIV) patients, often presenting asymptomatically. Regular thyroid function screening is recommended for individuals with HIV.
Area of Science:
- Endocrinology
- Infectious Diseases
- Virology
Background:
- Thyroid dysfunction is a frequent complication in patients with human immunodeficiency virus (HIV) infection.
- The causes of thyroid dysfunction in HIV-infected individuals are multifactorial.
Purpose of the Study:
- To investigate the prevalence and characteristics of thyroid dysfunction in patients with HIV.
- To assess the relationship between thyroid function and clinical parameters in HIV patients.
Main Methods:
- A cross-sectional study involved 127 adult patients infected with HIV.
- Thyroid function tests (TSH, free thyroxine), viral load, and CD4 counts were measured.
- Symptom questionnaires and exclusion criteria (endocrine disease, pregnancy) were applied.
Main Results:
- Hypothyroidism (13 cases), hyperthyroidism (1 case), and hypothyroxinemia (8 cases) were identified.
- No significant differences in symptoms, CD4 counts, or Hepatitis B co-infection were observed between patients with and without thyroid dysfunction.
- No association was found between antiretroviral therapy and thyroid dysfunction.
Conclusions:
- Thyroid abnormalities in HIV-infected patients are typically asymptomatic.
- Systematic thyroid function assessment is advisable for all patients with HIV.
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