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The ISN 0by25 Global Snapshot Study.

John Feehally¹

¹International Society of Nephrology, Brussels, Belgium.

Annals of Nutrition & Metabolism

|June 15, 2016

Summary

This summary is machine-generated.

The International Society of Nephrology

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Area of Science:

Nephrology
Epidemiology
Global Health

Background:

Acute kidney injury (AKI) causes preventable deaths, particularly in low and lower middle-income countries (LLMICs).
The International Society of Nephrology's (ISN) 0by25 initiative targets reducing AKI deaths by 2025.

Purpose of the Study:

To investigate the global epidemiology of AKI, with a focus on LLMICs.
To identify factors contributing to AKI and its outcomes worldwide.

Main Methods:

A multinational, cross-sectional study ('Global Snapshot') involving 322 physicians across 72 countries.
Identification and data collection on 4,018 patients (3,664 adults, 354 children) with AKI.

Main Results:

AKI patients in LLMICs were younger, with more community-acquired cases, dehydration, sepsis, and pregnancy-related causes.
Acute dialysis was underutilized in LLMICs due to resource limitations and cost.
Overall 7-day mortality was 11%, higher in LLMICs, though complete recovery was more frequent in these regions.

Conclusions:

The ISN 0by25 Global Snapshot provides crucial epidemiological data on AKI globally.
Findings highlight key areas for intervention to reduce preventable AKI deaths, especially in resource-limited settings.