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Personalized medicine. Closing the gap between knowledge and clinical practice.

Juan-Manuel Anaya1, Carolina Duarte-Rey1, Juan C Sarmiento-Monroy1

  • 1Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia.

Autoimmunity Reviews
|June 16, 2016
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Summary

Personalized medicine uses patient data and biotechnology for tailored healthcare. This approach, including P5 medicine, focuses on predicting and preventing diseases like rheumatoid arthritis and type 1 diabetes.

Keywords:
Autoimmune ecologyDeveloping countriesPharmacogenomicsPrecision medicineRheumatoid arthritisType 1 diabetes

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Area of Science:

  • Biomedical Sciences
  • Genomics
  • Systems Biology

Background:

  • Personalized medicine leverages individual patient data and biomarkers.
  • Terminology like 'precision medicine' and 'individualized medicine' is evolving.
  • A humanized approach integrates systems biology and P5 medicine concepts.

Purpose of the Study:

  • To present the process of personalized medicine.
  • To explore healthcare options within resource limitations.
  • To address diseases such as rheumatoid arthritis and type 1 diabetes.

Main Methods:

  • Utilizing systems biology and P5 medicine principles.
  • Examining predictive factors for disease development in populations.
  • Applying personalized and participatory healthcare models.

Main Results:

  • Personalized medicine aims to revert to a historical, patient-focused practice using modern tools.
  • P5 medicine emphasizes prediction, prevention, personalization, and participation.
  • Healthcare strategies are adaptable for resource-limited settings.

Conclusions:

  • Personalized medicine offers a framework for tailored, proactive healthcare.
  • Integrating P5 medicine enhances disease prediction and prevention.
  • The approach is applicable to chronic diseases like rheumatoid arthritis and type 1 diabetes, even with limited resources.