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Related Concept Videos

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Antiasthma Drugs: Leukotriene Modifiers01:19

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Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
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Antiasthma Drugs: Methylxanthines01:24

Antiasthma Drugs: Methylxanthines

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Theophylline, a member of the methylxanthine class of bronchodilators, has long been used in asthma management. While its exact mechanism of action is not fully understood, it is believed to have multiple effects on various cellular processes.
Theophylline is thought to inhibit phosphodiesterase enzymes, increasing intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). This rise in cAMP and cGMP concentrations stimulates cardiac function,...
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Antiasthma Drugs: Muscarinic Receptor Antagonists01:20

Antiasthma Drugs: Muscarinic Receptor Antagonists

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Muscarinic receptor antagonists, also known as antimuscarinic agents, are a class of bronchodilators used to treat asthma, although they are more commonly used to treat COPD. They work by inhibiting the action of acetylcholine (ACh), a neurotransmitter, on muscarinic receptors found in the airways.
Antimuscarinic agents compete with ACh for the same binding site on the muscarinic receptors. By binding to these receptors, they inhibit the downstream effects of ACh and block the parasympathetic...
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Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

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Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
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Inhaled Medications01:23

Inhaled Medications

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Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
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Related Experiment Video

Updated: Mar 19, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
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Mepolizumab.

Dennis J Cada, Ross J Bindler, Danial E Baker

    Hospital Pharmacy
    |June 16, 2016
    PubMed
    Summary

    The Formulary Monograph Service provides monthly drug monographs and utilization evaluations for Pharmacy & Therapeutics Committees. This service aids in informed drug selection and management for healthcare facilities.

    Area of Science:

    • Pharmacology
    • Drug Information Services
    • Healthcare Management

    Background:

    • The Formulary Monograph Service delivers essential drug information to healthcare professionals.
    • It supports Pharmacy & Therapeutics Committees in drug evaluation and formulary management.
    • The service includes monographs for new and investigational drugs, plus utilization evaluations.

    Purpose of the Study:

    • To provide timely and comprehensive drug information to subscribers.
    • To support evidence-based decision-making in medication management.
    • To offer customizable resources for healthcare facilities.

    Main Methods:

    • Publication of 5-6 detailed monographs on new or late-phase drugs monthly.
    • Inclusion of 1-page summary monographs for pharmacy and nursing in-services.

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  • Provision of a comprehensive drug utilization evaluation/medication use evaluation (DUE/MUE) each month.
  • Main Results:

    • Subscribers receive print and online access to monographs.
    • Customization options are available to meet specific facility needs.
    • A monthly drug class review is now included, with selected reviews published in Hospital Pharmacy.

    Conclusions:

    • The Formulary Monograph Service is a valuable resource for drug information and management.
    • It facilitates informed decisions regarding drug selection and utilization.
    • The service supports continuous learning and operational efficiency in pharmacy departments.