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SDH with Bleeding Diathesis-a Management Protocol
Gurneet Singh Sawhney1, Cecil R Ross2, Manmeet Singh Chhabra1
1Department of Neurosurgery, St. John's Medical College, Sarjapur Road, Bangalore, 560034 India.
Insights
Managing bleeding risk in elderly patients undergoing surgery for subdural hematoma (SDH) is crucial. This study found that specific blood product dosing and surgical techniques effectively prevented bleeding complications in patients on antiplatelet or anticoagulant medications.
Area of Science:
- Neurosurgery
- Hematology
Background:
- Chronic subdural hematoma (SDH) is a significant cause of morbidity and mortality in the elderly.
- Patients on antiplatelet or anticoagulant therapy face increased perioperative bleeding risks during SDH surgery.
Purpose of the Study:
- To evaluate the efficacy of precise blood product dosing and surgical techniques in preventing hemorrhagic complications in elderly patients with SDH on antiplatelet and/or anticoagulant medications.
Main Methods:
- A retrospective study of 25 elderly patients on antiplatelet and/or oral anticoagulants undergoing emergency SDH surgery between January 2010 and December 2012.
- Patients were categorized into three groups based on medication: antiplatelets only, oral anticoagulants only, or both.
- Interventions included minicraniotomy with microsurgical membranectomy or burr hole craniostomy, with administration of random donor platelet concentrate (RDPC) and/or fresh frozen plasma (FFP) based on medication use.
Main Results:
- No intraoperative bleeding complications or postoperative rebleeding occurred in any of the 25 patients.
- Patients on antiplatelets received a mean of 7 units of RDPC; those on oral anticoagulants received a mean of 4 units of FFP; and those on both received a mean of 7 units of RDPC and 4 units of FFP.
- All patients experienced successful intraoperative hemostasis and favorable postoperative outcomes regarding bleeding.
Conclusions:
- A specific protocol for blood product administration (RDPC for antiplatelets, FFP for anticoagulants) combined with tailored surgical approaches effectively prevents perioperative bleeding in SDH patients on antithrombotic therapy.
- This strategy ensures safe surgical management and reduces the risk of rebleeding in this high-risk patient population.
Abstract:
Chronic subdural hematoma (SDH) is one of the leading causes of morbidity and mortality in elderly. Patients taking antiplatelets and/or anticoagulants have increased risk of bleeding during the perioperative period. Precise dose blood products and specific surgical technique have been effective in preventing hemorrhagic complications perioperatively. From Jan 2010 to Dec 2012, 25 patients who were on antiplatelets and/or oral anticoagulants underwent emergency surgery for chronic or acute on chronic SDH. Patients were divided into three groups: group I-patients on antiplatelets, group II-patients on oral anticoagulants, and group III-patients taking both. Of these, 21 patients underwent minicraniotomy with microsurgical membranectomy and 4 patients underwent burr hole craniostomy. Random donor platelet concentrate (RDPC) and fresh frozen plasma (FFP) were used depending on whether patient was on antiplatelets or oral anticoagulants. Results were evaluated on the basis of ease of intraoperative hemostasis, incidence of rebleeding in postoperative period, postoperative imaging, and reversal of neurological deficits. Group I, group II, and group III had 16, 4, and 5 patients, respectively. Group I received a mean of 7 units of RDPC. Group II received a mean of 4 units of FFP. Group III received a mean of 7 units of RDPC and 4 units FFPs. There was no problem with intraoperative hemostasis and no incidence of rebleeding. We suggest specific dose protocol for reversal of antiplatelet and anticoagulant effect and specific surgical procedure in preventing intraoperative bleeding and postoperative rebleeding in the above group of patients.
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